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Tobacco Control and Tobacco Caused Cancers Pilot Projects

This year, the Hollings Cancer Center was able to fund projects for Tobacco Control and Tobacco Caused Cancer Research through the cigarette tax money received from the state of South Carolina. This funding opportunity was made available to researchers throughout the state. The same review process was used for these applications as for the Translational Research Pilot Projects. These projects were funded at or around $75,000 each.

Tobacco Control & Tobacco-Caused Cancer Pilot Projects

Name

Project Title

John Baatz & Demetri Spyropoulos, PhD, Department of Pediatrics and Pathology & Laboratory Medicine

Co-investigators/collaborators: George Simon, Patrick Flume

Viable Tissue Biorepository from Lung Lobectomy

Matthew Carpenter, PhD, Department of Psychiatry & Behavioral Health

Co-investigators/collaborators: Michael Cummings, Karen Cropsey, Katy Wynne, (DHEC), Gerard Silvestri, Kevin Gray, Bianca F. Jardin, Amy E. Wahlquist

A Pilot Translational Study of Sampling NRT for Cessation Induction: Is Motivation Necessary?

Terry Day, MD, Department of Otolaryngology

Co-investigators/collaborators: Steven Rosenzweig, Besim Ogretmen, Anthony Alberg, Matthew Carpenter, Marvella Ford, Marion B. Gillespie, Katherine D. Sterba, Elizabeth Garrett-Mayer

A Transdisciplinary Prospective Cohort Study to Understand the Root Causes of the Racial Disparity in HNSCC Survival

Campbell McInnes, PhD, Department of Pharmaceutical and Biomedical Sciences (USC)

Co-investigators/collaborators: Michael D. Wyatt, Charles D Smith, John Lazo, U.niversity of Virginia; Guillermo Montoya, Crystallography, Spanish National Cancer Institute

Selective Plk1 Anti-Tumor Therapeutics through Polo Box Domain Inhibition

Besim Ogretmen, PhD, Department of Biochemistry & Molecular Biology

Co-investigators/collaborators: George R. Simon, Yusuf A. Hannun, Elizabeth Garrett-Mayer, Angen Liu

Development of Targeted Therapeutics against SCLC

Dennis Watson, PhD, Department of Pathology & Laboratory Medicine

Co-investigators/collaborators: Patricia Watson, Chadrick E. Denlinger,  Angen Liu, Betsy Hill

Contribution of Alternative Splicing to Lung Cancer Progression

University of Colorado/MUSC NCI Lung SPORE

The HCC, through its collaboration with the University of Colorado/MUSC NCI Lung SPORE, awarded Eduardo Maldonado, PhD a career development award. Dr. Maldonado’s project was funded for $50,000.

Lung SPORE – Career Development Award

Name

Project Title

Eduardo Maldonado, DVM, PhD, Department of Pharmaceutical & Biomedical Sciences

John J. Lemasters

Drug Discovery Against Warburg Metabolism in Lung Cancer Cells

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