for Pre- and Post-Doctoral Trainees Kristen Champion, Graduate Student
Faculty Mentor: Tien Hsu, Ph.D.
Research:
Current therapies used in treatment of VHL tumors have been largely ineffective in clinical trials.
1) Demonstrate that loss-of-function of VHL in endothelial cells leads to increased cell motility.
2) Elucidate the cellular mechanism(s) that mediate VHL function within endothelial cells. Rebecca Bullard, Graduate Student
Faculty Mentor: Carlton Donald, Ph.D.
Research:
Specific Aim 1. Determine the cellular mechanisms associated with the effects of DEFBI on prostate cancer cells.
Specific Aim 2. Determine the role of DEFBI in the progression of prostate cancer. Victoria Findlay, Ph.D., Post-Doctoral Fellow
Faculty Mentor: Dennis Watson, Ph.D.
Research:
To determine the role of specific signaling pathways in the modulation of PDEF function during breast cancer progression.
1) Examine the cellular effects of EGF modulated PDEF expression.
2) Examine the effects of PDEF phosphorylation on cellular function. Yong Wang, Ph.D., Post-Doctoral Fellow
Faculty Mentor: Daohong Zhou, Ph.D.
Research:
The ultimate goal of the project is to elucidate the mechanisms underlying chemotherapy and radiotherapy induced residual BM injury in cancer patients. This will lead to the discovery of novel molecular targets for intervention to circumvent chemotherapy. Russell Jenkins, MSTP
Faculty Mentor: Yusuf Hannun, M.D. Linda Heffernan, MSTP
Faculty Mentor: Lina Obeid | 
