MUSC Hollings Cancer Center

Stephen P. Ethier, PhD

EitherDr. Stephen P. Ethier joined the Hollings Cancer Center in 2012 as the Countess Alicia Spaulding-Paolozzi Distinguished Endowed Chair for Breast Cancer Diagnosis, Treatment and Research.  He is also Professor of Pathology & Laboratory Medicine and the current Director of MUSC’s Center for Genomic Medicine.  Dr. Ethier’s long-term research interests are focused on the cellular and molecular mechanisms of breast cancer development. He has made major contributions to the understanding of the mechanisms by which the HER-2 oncogene transforms rodent and human mammary epithelial cells. In addition, he developed the SUM series of breast cancer cell lines that includes nearly all of the molecular subtypes of human breast cancer and represents an essential resource for the international breast cancer community. In a natural progression, Dr. Ethier’s laboratory expanded its focus to include research in breast cancer genomics. His laboratory has played a leading role in identifying the key oncogenes that drive the maintenance of the 8p11 amplicon, which occurs in about 15% of breast cancers.

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