Cellular Therapy Core PDF *MNA User Authetication Required

Director
David J. Cole, MD
Professor of Surgery

Co-Medical Director
Zihai Li, MD, PhD
Professor of Microbiology & Immunology

Associate Scientific Directors
Shikhar Mehrotra, PhD
Assistant Professor of Surgery
Hongjun Wang, PhD
Associate Professor of Surgery 

Contact Information

Mingli Li
Phone: 843-792-6165
E-Mail: limingli@musc.edu
Location: 2nd Floor Clinical Sciences Building, within the GCRC

Description
The Cellular Therapy shared resource is an interdepartmental initiative to facilitate a variety of cell-based therapies requiring cell and tissue processing in a clean room environment.  It will be a cell processing facility in accordance with Good Manufacturing Practice (cGMP) and Good Tissue Practice (cGTP) standards in order to support multiple investigator-initiated (IND), industry-sponsored Investigational New Drug/Investigations Device Exemption (IDE) and standard clinical care protocols to include:

• Processing autologous pancreatic islet cells for transplantation
• Processing and isolating hepatocytes
• Generation of Dendritic cells for cancer vaccines
• Hematopoietic stem cell expansion protocols
• Gene transduction into dendritic or stem cell populations
• Tumor cell and T-cell purging protocols using human hematopoietic stems cells
• Cell-based immune therapy protocols involving plasmid/viral transduced human cells
• Cell processing to facilitate the fabrication of engineered tissues.