Lipidomics - Analysis Unit
Director
Alicja Bielawska, PhD
Professor of Biochemistry & Molecular Biology
Manager and Lead Scientist
Jacek Bielawski, PhD
Associate Professor of Biochemistry & Molecular Biology Contact Information
Alicja Bielawaska, PhD
Phone: 843-792-0273
E-Mail: bielawsk@musc.edu
Location: 535 Basic Science Building (BSB) Jacek Bielawski, PhD
Phone: 843-792-1529
E-Mail: bielawsj@musc.edu
Location: 502 Children's Research Institute (CRI) Description The Hollings Cancer Center (HCC) Lipidomics Shared Resource represents a novel scientific service that is unique to the Medical University of South Carolina.The Lipidomics Shared Resource builds on unique expertise at MUSC in sphingolipid biology, chemistry and analysis and their role in signal transduction and cell regulation. Sphingolipid metabolism assumes a key role in the complex mechanisms regulating cellular stress responses to environmental changes. Several sphingolipid metabolites act as bioactive molecules, and their individual contribution to the regulatory pathways that govern cell growth are being established. This offers promises for new molecular insights into tumor growth and metastasis and emphasizes the needs to analyze sphingolipid components, examine sphingolipid chemistry and regulation of sphingolipid metabolic pathways. Monitoring changes in sphingolipid composition in normal and cancer environments will provide one of the missing links in the search for a novel and effective therapy. Services Please visit our Lipidomics - Analysis Unit Shared Resource website for a comprehensive list of services and fees. Equipment - Four ThermoFisher TSQ Quantum triple-stage quadrupole mass spectrometers with super high pressure HPLC system, ESI and APCI probes came online to assist with increase in demand
- 1100HP/ThermoFinnigan TSQ 7000TM triple-stage quadrupole mass spectrometer LC/MS system, ESI and APCI probes.
- 1100HP/SCIEX 2000 Q-Trap triple-stage quadrupole/ion trap combination mass spectrometer LC/MS combo, ESI and APCI probes.
- Berger FCM 1200 Supercritical Fluid Chromatograph (SCF)
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86 Jonathan Lucas Street 
