The Cellular Therapy shared resource is an interdepartmental initiative to facilitate a variety of cell-based therapies requiring cell and tissue processing in a clean room environment. It will be a cell processing facility in accordance with Good Manufacturing Practice (cGMP) and Good Tissue Practice (cGTP) standards in order to support multiple investigator-initiated (IND), industry-sponsored Investigational New Drug/Investigations Device Exemption (IDE) and standard clinical care protocols to include:
- Processing autologous and allogeneic pancreatic islet cells for transplantation
- Processing and isolating hepatocytes
- Generation of Dendritic cells for cancer vaccines
- Hematopoietic stem cell expansion protocols
- Gene transduction into dendritic or stem cell populations
- Tumor cell and T-cell purging protocols using human hematopoietic stems cells
- Cell-based immune therapy protocols involving plasmid/viral transduced human cells
- Cell processing to facilitate the fabrication of engineered tissues.
